Question

Open vial policy is NOT applied to which vaccine?

• A. Hepatitis B
• B. Liquid pentavalent vaccine
• C. BCG vaccine
• D. OPV vaccine

Hint:

The open vial policy is applicable only to vaccines that can remain stable and sterile over multiple sessions, such as Hepatitis B and OPV.

Answer 1

The Correct Option is C

The open vial policy allows the use of certain vaccines in multiple sessions within a specified time period if the vial is handled under appropriate cold chain conditions. However, it does not apply to vaccines like BCG, as it is a freeze-dried (lyophilized) vaccine and must be discarded within 4–6 hours after reconstitution to prevent contamination and maintain efficacy.