Question:

One of the parents of a cross has mutation in its mitochondrion. In that cross, that parent is taken as male. During segregation of $F_2$ progenies that mutation is found in

Updated On: Apr 14, 2025
  • One third of the progenies
  • None of the progenies
  • All the progenies
  • Fifty percent of the progenies
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The Correct Option is B

Solution and Explanation

Mutation is a sudden alteration of the chemical structure of a gene or the alteration of its position on the chromosome by breaking and rejoining of the chromosome. It has occured in male parent. But organelles like mitochondria, chloroplast etc. are a part of cytoplasmic inheritance. Cytoplasmic inheritance is the passage of traits from parents to offspring through structures present inside the cytoplasm of contributing gametes. Plasma genes occur in plastids, mitochondria, plasmids and some special particles like kappa particles, sigma particles, etc. In higher organisms cytoplasmic inheritance is called maternal inheritance because the zygote receives most of its cytoplasm from the ovum. Therefore, cytoplasmic inheritance is usually unparental.So none of the progeny will show mutation.
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Concepts Used:

Principles of Inheritance and Variation - Mutation

A Mutation is a change in the sequence of our DNA base pairs caused by numerous environmental stimuli such as UV light or mistakes during DNA replication. Germline mutations take place in the eggs and sperm and can be passed onto offspring, whereas somatic mutations take place in body cells and are not passed on.

Types of Mutations

There are three types of mutations, which are as follows:

Silent mutation

It refers to any change in DNA sequence that has no effect on the amino acid sequence in a protein or the functions that a protein performs. There is no phenotypic indication that a mutation has occurred.

Nonsense mutation

When there is a change in the sequence of base pairs due to a point mutation, that results in a stop codon. This leads to a protein that is either shortened or non-functional.

Missense mutation

A missense mutation occurs when a point mutation causes a change in the codon, which then codes for another amino acid.

The mutation is caused by the following factors:

Internal Causes

When DNA copies incorrectly, the majority of mutations occur. Evolution occurs as a result of all of these mutations. DNA makes a copy of itself during cell division. When a copy of DNA isn't flawless, it's called a mutation since it differs somewhat from the original DNA.

External Causes

When certain chemicals or radiations are used to break down DNA, it causes the DNA to break down. The thymine dimers are broken by UV radiation, resulting in altered DNA.