Question:
Nucleotides in RNA are joined by which of the following phosphodiester linkages?
Nucleotides in RNA are joined by which of the following phosphodiester linkages?
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Remember: both DNA and RNA have 5$'$–3$'$ phosphodiester linkages.
Updated On: Jan 5, 2026
- 5$'$–3$'$
- 5$'$–2$'$
- 3$'$–2$'$
- 3$'$–3$'$
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The Correct Option is A
Solution and Explanation
In RNA, each nucleotide is linked to the next through a phosphodiester bond.
This bond forms between the 3$'$–OH of one sugar and the 5$'$–phosphate of the next nucleotide.
Thus, the linkage is called a 5$'$–3$'$ phosphodiester bond.
This bond forms between the 3$'$–OH of one sugar and the 5$'$–phosphate of the next nucleotide.
Thus, the linkage is called a 5$'$–3$'$ phosphodiester bond.
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