Question:
Most common mutation in Papillary cell carcinoma?
Most common mutation in Papillary cell carcinoma?
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BRAF V600E mutation is a significant marker for papillary thyroid carcinoma and can help in diagnosis and targeted therapy.
Updated On: Mar 24, 2025
- BRAF V600E
- RET
- MET
- RAS
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The Correct Option is A
Solution and Explanation
BRAF V600E mutation is the most common genetic alteration observed in papillary thyroid carcinoma, especially in the classic variant of the disease. This mutation leads to the activation of the MAPK/ERK signaling pathway, contributing to cancer progression.
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