Question:

Match the molecules in Column-I with their correct property/function in Column-II

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{RNA Polymerase-I} is involved in rRNA transcription, while {siRNA} helps with gene silencing. {Guide RNA} is essential for genome editing using Cas9, and {RNase P} plays a role in tRNA processing.
Updated On: May 5, 2025
  • P - 4 ; Q - 5 ; R - 2 ; S - 3
  • P - 5 ; Q - 1 ; R - 3 ; S - 4
  • P - 4 ; Q - 1 ; R - 2 ; S - 3
  • P - 1 ; Q - 3 ; R - 4 ; S - 2
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The Correct Option is C

Solution and Explanation

The correct matching between the molecules and their functions is as follows:

- RNase P (P): RNase P is an enzyme responsible for processing precursor tRNA molecules. It plays a critical role in tRNA gene transcription. Therefore, P matches with 4 (Ribozymes).

- RNA Polymerase-I (Q): RNA Polymerase-I is responsible for transcribing rRNA genes. Therefore, Q matches with 1 (rRNA gene transcription).

- siRNA (R): siRNA (small interfering RNA) is involved in gene silencing by promoting the degradation of target mRNA. Therefore, R matches with 2 (Gene silencing).

- Guide RNA (S): Guide RNA is used in Cas9-mediated genome editing, where it directs the Cas9 endonuclease to a specific DNA sequence for editing. Therefore, S matches with 3 (Cas9-mediated genome editing).

Thus, the correct answer is option (C).
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