The correct matching between the molecules and their functions is as follows:
- RNase P (P): RNase P is an enzyme responsible for processing precursor tRNA molecules. It plays a critical role in tRNA gene transcription. Therefore, P matches with 4 (Ribozymes).
- RNA Polymerase-I (Q): RNA Polymerase-I is responsible for transcribing rRNA genes. Therefore, Q matches with 1 (rRNA gene transcription).
- siRNA (R): siRNA (small interfering RNA) is involved in gene silencing by promoting the degradation of target mRNA. Therefore, R matches with 2 (Gene silencing).
- Guide RNA (S): Guide RNA is used in Cas9-mediated genome editing, where it directs the Cas9 endonuclease to a specific DNA sequence for editing. Therefore, S matches with 3 (Cas9-mediated genome editing).
Thus, the correct answer is option (C).