Question

Match List I with List II

List I		List II
A	Frederick Griffith	I	Genetic code
B	Francois Jacob & Jacque	II	Semi-conservative mode of DNA replication
C	Har Gobind Khoran	III	Transformation
D	Meselson & Stahl	IV	Lac operon

Choose the correct answer from the options given below:

• A. A-III, B-II, C-I, D-IV
• B. A-III, B-IV, C-I, D-II
• C. A-II, B-III, C-IV, D-I
• D. A-IV, B-I, C-II, D-III

Answer 1

The Correct Option is B

To correctly match the items from List I with List II, let's analyze the contributions of each scientist mentioned:

• Frederick Griffith is renowned for discovering the phenomenon of Transformation, a process where genetic material from one cell is taken up by another cell, often altering its genetic makeup.
• Francois Jacob and Jacques Monod are credited with developing the concept of the Lac operon, a model explaining gene regulation in bacteria.
• Har Gobind Khorana was pivotal in deciphering the Genetic code, showing how sequences of nucleotides correspond to specific amino acids.
• Meselson and Stahl demonstrated the Semi-conservative mode of DNA replication, where each new DNA molecule retains one original strand and one new strand.

Based on these explanations, the correct matching is:

List I		List II
A	Frederick Griffith	III	Transformation
B	Francois Jacob & Jacques Monod	IV	Lac operon
C	Har Gobind Khorana	I	Genetic code
D	Meselson & Stahl	II	Semi-conservative mode of DNA replication

Therefore, the correct answer is: A-III, B-IV, C-I, D-II.

Answer 2

A. Frederick Griffith is known for his discovery of the phenomenon of transformation, so it matches with III. Transformation.

B. Francois Jacob & Jacque Monod are known for their work on the Lac operon, so it matches with IV. Lac operon.

C. Har Gobind Khorana is credited with deciphering the genetic code, so it matches with I. Genetic code.

D. Meselson & Stahl are famous for their experiment demonstrating the semi-conservative model of DNA replication, so it matches with II. Semi-conservative mode of DNA replication.

Thus, the correct answer is (2) A-III, B-IV, C-I, D-II.