Step 1: Identifying challenges with carbon nanotubes.
The large-scale use of carbon nanotubes faces several issues:
- (A) Synthesizing carbon nanotubes in pure forms is challenging.
- (B) Dispersion in solvents is difficult due to their strong tendency to clump together.
- (C) Reducing their length is necessary for certain applications but is hard to achieve consistently.
- (D) Tailoring their orientation is essential for specific applications, but this is not always feasible.
Final Answer:
\[
\boxed{3. \text{(A), (B), (C), and (D)}}
\]