1. Damage to Nervous System and Liver: Chronic use of alcohol damages the central nervous system and leads to liver cirrhosis.
2. Social and Family Problems: Abuse leads to reckless behavior, vandalism, and violence. It often results in the deterioration of personal relationships and financial distress for the family.
3. Health Risks from Injections: Intravenous drug users are at high risk of contracting serious infections like AIDS and Hepatitis B through shared needles.
4. Mental Health Issues: Drug and alcohol abuse can lead to depression, anxiety, fatigue, and in extreme cases, permanent damage to brain function or even coma and death due to respiratory failure.