Question:

Individuals with karyotype of 44+XXY having overall masculine development with few feminine development like Gynaecomastia has _______ chromosomal disorder.

Updated On: Jun 2, 2024

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The Correct Option is A

The correct option is (A): Klinefelter’s Syndrome

Klinefelter’s Syndrome

Klinefelter's syndrome is a genetic condition characterized by an additional X chromosome -XXY on the sex chromosome.
Because of the additional X chromosome, estrogen secretion is high, resulting in sterility, but overall masculine development.

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Reproduction in human beings involves the fusion of male and female gametes that produces in their reproductive system.

The male reproductive system comprises:

Testicles (testes): A pair of oval-shaped organs masked in a pouch known as the scrotum. They manage the production of sperms and the male hormone testosterone.
Scrotum: It is a sac-like organ that hangs under the penis and behind it. It is the house of the testes, or testicles, and maintains a temperature that is needed for the production of sperm by it.
Vas deferens: The sperms produced in testes are stored in a tube known as the epididymis. Here the sperms get matured and pass to the urethra via the muscular tube known as vas deferens.
Accessory glands: This includes three glands, namely the prostate gland, seminal vesicles, and Cowper’s gland. The secretions from the mentioned three glands mix to form a fluid known as semen. Semen nourishes the sperm, raises the volume, and helps in lubrication.
Penis: The penis is a cylindrical tube that serves as both an excretory organ, and a reproductive organ. It transfers sperms into the vagina during sexual intercourse.

The female reproductive system is active before, during, and after fertilization as well. It comprises the following parts:

A pair of ovaries: A pair of ovaries produce and stores ovum in them. They also produce a female hormone known to be estrogen.
Fallopian tubes (Oviducts): They are the area of fertilization. They connect both the ovaries with the uterus.
Uterus: Uterus is the place of development for the embryo.
Vagina: The part that connects the cervix to the external female body parts is called a vagina. It is the passage for the penis during coitus as well as a fetus during transfer.

List - I (Structures)		List – II (Features)
A.	Mons pubis	i.	A fleshy fold of tissue surrounding the vaginal opening
B.	Clitoris	ii.	Fatty cushion of cells covered by skin and hair
C.	Hymen	iii.	Tiny finger-like structure above labia minora
D.	Labina majora	iv.	A thin membrane-like structure covering vaginal opening

List - I		List – II
A.	Parturition	i.	Several antibodies for new-born babies
B.	Placenta	ii.	Collection of ovum after ovulation
C.	Colostrum	iii.	Foetal ejection reflex
D.	Fimbriae	iv.	Secretion of the hormone hCG