Question

In the reaction of hypobromite with amide, the carbonyl carbon is lost as :

• A. CO
• B. CO₂
• C. CO₃²⁻
• D. HCO₃⁻

Hint:

Hoffmann degradation "descends" the series by one carbon atom, turning an amide into a primary amine with one less carbon.

Answer 1

The Correct Option is C

Step 1: The reaction is the Hoffmann Bromamide Degradation. The general equation is: \[ R-CONH_2 + Br_2 + 4NaOH \rightarrow R-NH_2 + Na_2CO_3 + 2NaBr + 2H_2O \]
Step 2: The carbonyl carbon (\(C=O\)) of the amide is removed. Since the reaction takes place in a basic medium (\(NaOH\)), the carbon is eliminated as the carbonate ion (\(CO_3^{2-}\)).