In the given pedigree chart, ‘P’ is a female suffering from a disease, which is denoted by ‘A’ (dominant allele) and ‘a’ (recessive allele). Find the genotype of ‘P’.
In a pedigree chart analysis, we need to determine the genotype of 'P', who is a female showing a disease. The disease present in ‘P’ is denoted by a recessive allele 'a'. To deduce the genotype of 'P', we consider the following points:
Inheritance Pattern: A disease caused by a recessive allele will only manifest in an individual if they have two copies of the allele, i.e., they are homozygous recessive ('aa').
Pedigree Analysis: Since 'P' is suffering from the disease, she must be homozygous for the recessive allele. This means 'P' can only have the genotype 'aa'.
Conclusion: As the disease is present in 'P' and is determined by a recessive allele, her genotype is inevitably 'aa'.
Therefore, the correct genotype of 'P', given that she is affected by the recessive disease, is aa.
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Approach Solution -2
P is a female suffering from a disease that is caused by a recessive allele (denoted as 'a').
In order for P to express the disease caused by a recessive allele, she must have two copies of the recessive allele (aa). Since P is affected by the disease, her genotype must be aa.
