The electric field is the negative gradient of the electric potential:
$$ \vec{E} = - \nabla V $$
Given that $V = 20|r|$, the gradient of $V$ is $\nabla V = 20 \hat{r}$, where $\hat{r}$ is the unit vector in the direction of $\vec{r}$. Substituting the coordinates $(4, 3, -5)$, we get the electric field as $-\sqrt{2} (8i + 6j - 10k)$.