Question

In N-linked glycoproteins, carbohydrate moiety is attached to which of the following amino acids?

• A. Valine
• B. Asparagine
• C. Serine
• D. Threonine

Hint:

N-linked glycosylation attaches glycans to the nitrogen atom of the asparagine side chain. Remember: "N" for AsparagiNe.

Answer 1

The Correct Option is B

Step 1: Understand N-linked glycosylation. 
N-linked glycosylation is a common post-translational modification in which a carbohydrate (glycan) is attached to the nitrogen atom in the side chain of a specific amino acid. 
Step 2: Identify the target amino acid. 
In N-linked glycosylation, the carbohydrate is attached to the amide nitrogen of the asparagine residue within a specific consensus sequence (Asn-X-Ser/Thr, where X is any amino acid except proline). 
Step 3: Eliminate incorrect options. 
Valine does not participate in glycosylation.
Serine and Threonine are involved in O-linked glycosylation (attachment to hydroxyl group).
Asparagine is the correct residue for N-linked glycosylation.