Question:

In mice, a trait is determined by a dominant allele Y and recessive allele y. What proportion of the offspring from a YY × yy cross is expected to be homozygous recessive in F1 generation?

Updated On: Nov 18, 2025
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The Correct Option is A

Solution and Explanation

To determine the proportion of the offspring from a YY × yy cross that is expected to be homozygous recessive in the F1 generation, we need to understand the basic principles of Mendelian genetics. Here’s a step-by-step explanation:

  1. Identify the Alleles:
    • The dominant allele is Y, which determines the dominant trait when present.
    • The recessive allele is y, which determines the recessive trait only when the allele is in homozygous condition (yy).
  2. Determine the Genotypes of Parents:
    • The genotype of the first parent is YY. 
    • The genotype of the second parent is yy.
  3. Set Up the Punnett Square:
    A Punnett square helps visualize the possible genotypes of the offspring.
     
 YY
yYyYy
yYyYy

All offspring will be Yy (heterozygous).

  1. Analyze the Results:
    • From the Punnett square, all F1 offspring have the genotype Yy.
    • Since none of the offspring have the genotype yy, there are zero homozygous recessive individuals.
  2. Conclusion:
    The proportion of homozygous recessive (yy) offspring in the F1 generation is 0.

Therefore, the correct answer is 0.

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