Question:

In ACLS which drug can be given following ventricular fibrillation after cardiac arrest other than epinephrine?

Updated On: Jul 11, 2025
  • Amiodarone
  • Dopamine
  • Adenosine
  • Atropine
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The Correct Option is A

Solution and Explanation

In Advanced Cardiovascular Life Support (ACLS), the primary focus during a ventricular fibrillation (VF) cardiac arrest is to restore a normal heart rhythm. The first-line drug used universally is epinephrine. Following epinephrine administration, if ventricular fibrillation persists, amiodarone is the recommended medication.
Explanation:
  • Epinephrine: Administered initially due to its vasoconstrictive effects, which improve coronary and cerebral perfusion during cardiopulmonary resuscitation (CPR).
  • Amiodarone: Given when VF is unresponsive to initial defibrillation attempts and epinephrine. It is an antiarrhythmic medication that works by prolonging the action potential and refractory period in cardiac tissues, thereby helping to restore an organized rhythm.
DrugIndication in VF After Cardiac Arrest
AmiodaroneGiven after epinephrine if VF persists
DopamineUsed in shock states, not indicated immediately in VF
AdenosineUsed for supraventricular tachycardia, not VF
AtropineUsed for bradycardia, not VF
Therefore, the correct drug to be given after ventricular fibrillation cardiac arrest, other than epinephrine, is Amiodarone.
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