Hyperacute graft rejection is an immediate immune response against a transplanted organ or tissue. This type of rejection is driven by pre-existing antibodies in the recipient that recognize antigens on the donor tissue. Upon contact, these antibodies bind to the vascular endothelium of the graft, initiating a series of events, including the activation of the complement cascade and rapid clot formation.
The key characteristic of hyperacute rejection is its swift onset, occurring within minutes of transplantation. This rapid reaction results in severe inflammation and thrombosis that can compromise graft viability almost instantly.
Given the options provided:
The correct answer is: In minutes.
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