Question:

Given below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: ATP is used at two steps in glycolysis. 
Reason R: First ATP is used in converting glucose into glucose-6-phosphate and second ATP is used in conversion of fructose-6-phosphate into fructose-1-6-diphosphate.
In the light of the above statements, choose the correct answer from the options given below:

Updated On: Aug 12, 2024
  • Both A and R are true but R is NOT the correct explanation of A.
  • A is true but R is false.
  • A is false but R is true.
  • Both A and R are true and R is the correct explanation of A.
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The Correct Option is D

Approach Solution - 1

Assertion A is true because ATP is indeed used at two steps in glycolysis. These steps are the conversion of glucose to glucose-6-phosphate, and the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate. In both of these steps, a phosphate group is added to the substrate, and ATP is used to provide the phosphate group.
Reason R is also true and provides the correct explanation for Assertion A. The first ATP is used in the conversion of glucose to glucose-6-phosphate, and the second ATP is used in the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate. Therefore, Reason R correctly explains why ATP is used at two steps in glycolysis.

Therefore, The correct answer is (D): Both A and R are true and R is the correct explanation of A.

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Approach Solution -2

The assertion A is true because ATP (adenosine triphosphate) requires two major steps in glycolysis. These steps are:
1. Conversion of glucose to glucose-6-phosphate
2. Conversion of fructose-6-phosphate to fructose-1,6-bisphosphate.
In both these steps, a phosphate group is added to the substrate, and ATP is used to provide the phosphate group
The reason R is true and provides the correct explanation of A. In glycolysis, the first step is the conversion of glucose to glucose-6-phosphate catalyzed by the reaction hexokinase. The second step involves the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate catalyzed by phosphofructokinase. 
ATP (adenosine triphosphate) requires two major steps
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Concepts Used:

Glycolysis

What is Glycolysis?

It is the process in which glucose is broken down to produce energy. It produces two molecules of pyruvate, ATP, NADH and water. If the process takes place in cytoplasm of a cell and it does not require oxygen. It occurs in both aerobic and anaerobic organisms.

Glycolysis Pathway