Question:

Identify the step in tricarboxylic acid cycle, which does not involve oxidation of substrate.

Updated On: Mar 27, 2025
  • Malic acid→ Oxaloacetic acid
  • Succinic acid→ Malic acid
  • Succinyl-CoA→Succinic acid
  • Isocitrate→α-ketoglutaric acid
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The Correct Option is C

Solution and Explanation

The reaction Succinyl-CoA → Succinic acid does not involve oxidation. This step is a substrate-level phosphorylation where CoA is removed and the energy is used to form ATP or GTP.

The other reactions, like Isocitrate → α-ketoglutaric acid, involve oxidation as electrons are transferred to NAD+ to form NADH.

Thus, the correct answer is (3) Succinyl-CoA → Succinic acid.

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