Question:

Franklin Conrat demonstrated that RNA is the genetic material of

Updated On: Jun 21, 2022
  • HIV
  • TMV
  • CMV
  • Mouse sarcoma
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The Correct Option is B

Solution and Explanation

H. Fraenkel .Conrat and B. Singer demonstrated that RNA is a genetic material of TMV or tobacco mosaic virus by their experiments published in 1957.
They first developed the techniques for separating TMV ? particles into RNA and proteins. Later by .using RNA and proteins separated in tests for infectivity, they demonstrated that RNA alone was able to cause infection. They developed techniques for forming reconstructed viruses containing the protein from one mutant strain of TMV. and RNA from another, or vice-versa. Such hybrid viruses or chimeras were allowed to infect tobacco leaves and the progeny were examined. In all cases the progeny were the parental RNA type and not the parental protein type.
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Concepts Used:

The Molecular Basis of Inheritance

DNA Replication:

DNA synthesis is commenced at particular points within the DNA strand referred to as ‘origins’, which are certain coding regions. There are numerous origin sites, and when replication of DNA starts, these sites are mentioned as replication forks. Within the replication, the complex is the enzyme DNA Helicase, so that they can be utilized as a template for replication. DNA Primase is another enzyme that's essential in DNA replication.

RNA:

Ribonucleic acid (RNA) is an essential biological macromolecule that exists all together in biological cells. It is principally involved in the synthesis of proteins, that carry the messenger instructions from DNA, which itself contains the genetic instructions needed for the event and maintenance of life. In some viruses, RNA, in spite of DNA, carries genetic information.

Genetic Code:

Genetic code is the term we use in the manner that the four bases of DNA--the A, C, G, and Ts--are strung together in a way that the ribosome, the cellular machinery, can read them and switch them into a protein. In the ordering, every three nucleotides during a row count as a triplet and code for one amino alkanoic acid.

Read More: Molecular Basis of Inheritance