Question

Example for amino amide local anaesthetic agent is _______

• A. \( \text{Tetracaine} \)
• B. \( \text{Benzocaine} \)
• C. \( \text{Chloroprocaine} \)
• D. \( \text{Lidocaine} \)

Hint:

Remember the "i" before the "-caine" suffix often indicates the presence of an amide linkage (e.g., lidocaine, prilocaine, bupivacaine), while those without it are often esters (e.g., benzocaine, procaine, tetracaine).

Answer 1

The Correct Option is D

Local anaesthetics are broadly classified into two main groups based on their chemical structure: amino esters and amino amides. Lidocaine is a classic example of an amino amide local anaesthetic. The presence of an amide linkage (-NHCO-) in its structure distinguishes it from amino ester local anaesthetics like tetracaine, benzocaine, and chloroprocaine, which contain an ester linkage (-COO-). Amino amide local anaesthetics generally have a longer duration of action and are metabolized in the liver.