Question

Drug of choice for invasive aspergillosis is

• A. Posaconazole
• B. Voriconazole
• C. Liposomal AMB
• D. Caspofungin

Answer 1

The Correct Option is B

In pharmacology, the treatment of invasive aspergillosis is critical due to its serious nature, often occurring in immunocompromised individuals. The drug of choice for this condition is Voriconazole. Voriconazole is favored due to its efficacy, improved survival rates, and its ability to inhibit the synthesis of ergosterol, an essential component of fungal cell membranes. Alternative treatments exist, such as Liposomal Amphotericin B and Caspofungin, but Voriconazole remains the preferred option because of its effectiveness as a first-line therapy. Understanding the selection criteria for antifungal treatments emphasizes the importance of optimizing patient outcomes in cases of severe fungal infections.