Question

DOC of prophylaxis for motion sickness ?

• A. Promethazine
• B. Prochlorperazine
• C. Metoclopramide
• D. Itopride

Answer 1

The Correct Option is A

To determine the drug of choice (DOC) for prophylaxis of motion sickness, let us analyze the options provided:

1. Promethazine: An antihistamine with antiemetic properties effective in preventing motion sickness.

2. Prochlorperazine: Primarily used as an antiemetic for nausea and vomiting, but not specifically indicated for motion sickness prevention.

3. Metoclopramide: Acts on the central nervous system to treat nausea but is not typically used for motion sickness.

4. Itopride: A prokinetic agent used mainly for gastrointestinal problems and not for motion sickness.

Considering the pharmacological actions of these drugs, Promethazine is the recommended choice for the prophylaxis of motion sickness due to its efficacy in counteracting the vestibular system disturbances, which are a key component of this condition.

Therefore, the correct answer is Promethazine.