Question

DOC for Cyclosporiasis?

• A. Trimethoprim sulfamethoxazole combination
• B. Paromomycin
• C. Metronidazole
• D. Cyclosporin

Answer 1

The Correct Option is A

In the treatment of cyclosporiasis, the drug of choice (DOC) is crucial for effective management. Cyclosporiasis is a parasitic infection caused by Cyclospora cayetanensis. The prescribed treatment for this condition is the antibiotic combination known as Trimethoprim sulfamethoxazole (TMP-SMX). This combination is effective due to its synergistic action in inhibiting the bacterial folate synthesis pathway, which is a key factor in the growth and replication of Cyclospora. To clarify the options:

• Trimethoprim sulfamethoxazole combination: This is the correct choice, as it effectively treats cyclosporiasis by targeting the folate pathway of the parasite.
• Paromomycin: While it is an antiparasitic agent, it is not the primary treatment for cyclosporiasis.
• Metronidazole: Typically used for anaerobic bacteria and protozoa, it is not effective against Cyclospora.
• Cyclosporin: This is an immunosuppressant, not related to the treatment of cyclosporiasis.

To conclude, the recommended treatment for cyclosporiasis is the Trimethoprim sulfamethoxazole combination.