\[
\begin{array}{|c|c|}
\hline
\textbf{Plasmid DNA} & \textbf{Chromosomal DNA} \\
\hline
\text{Small, circular DNA found in bacteria} & \text{Large, linear DNA found in the nucleus} \\
\text{Carries non-essential genes} & \text{Carries essential genes} \\
\text{Self-replicating independently} & \text{Replicates with cell division} \\
\hline
\end{array}
\]