Step 1: Background.
Gregor Mendel, the father of genetics, conducted experiments on garden pea plants (Pisum sativum) to study the inheritance of traits. From his experiments, he proposed three laws of inheritance:
\begin{enumerate}
\item Law of Dominance
\item Law of Segregation
\item Law of Independent Assortment
\end{enumerate}
Here, we focus on the Law of Dominance.
Step 2: Statement of the law.
The Law of Dominance states that when two different alleles of a character are present in an organism (heterozygous condition), only one allele expresses itself (dominant), while the other allele remains masked (recessive).
Step 3: Example of Mendel's experiment.
Mendel crossed pure tall plants (\(TT\)) with pure dwarf plants (\(tt\)):
\[
TT \times tt \;\;\;\; $\Rightarrow$ \;\;\;\; F_1 \text{ generation: all } Tt
\]
All plants in the F1 generation were tall, showing that tallness (T) is dominant over dwarfness (t).
Step 4: Punnett Square.
\[
\begin{array}{|c|c|c|}
\hline
& T & T
\hline
t & Tt & Tt
\hline
t & Tt & Tt
\hline
\end{array}
\]
All F1 hybrids are tall (Tt), proving that the dominant trait (Tallness) masks the recessive trait (Dwarfness).
Step 5: Importance of the law.
\[\begin{array}{rl} \bullet & \text{Explains why certain traits appear in the F1 generation and why recessive traits reappear in the F2 generation.} \\ \bullet & \text{Foundation of classical genetics, used to predict inheritance patterns.} \\ \bullet & \text{Helps in plant and animal breeding to select desirable traits.} \\ \end{array}\]
Step 6: Limitation.
The law of dominance does not explain incomplete dominance or codominance, where both alleles may express partially or equally (e.g., flower colour in snapdragon, ABO blood groups in humans).
1. Perform a cross between two sickle cell carriers. What ratio is obtained between carrier, disease free and diseased individuals in F1 progeny? Name the nitrogenous base substituted, in the haemoglobin molecule in this disease.
2. Explain the difference in inheritance pattern of flower colour in garden pea plant and snap-dragon plant with the help of monohybrid crosses.
OR,
Explain with the help of well-labelled diagrams how lac operon operates in E. coli :
1. In presence of an inducer.
2. In absence of an inducer.
Study the pedigree chart given below, showing the inheritance pattern of blood group in a family:

Answer the following questions:
(a) Give the possible genotypes of individual 1 and 2.
(b) Which antigen or antigens will be present on the plasma membranes of the R.B.Cs of individuals ‘5’ and ‘8’?
The sequence of nitrogenous bases in a segment of a coding strand of DNA is
5' – AATGCTAGGCAC – 3'. Choose the option that shows the correct sequence of nitrogenous bases in the mRNA transcribed by the DNA.