Pyridoxine, also known as Vitamin B6, is essential for the proper functioning of the nervous system. It plays a critical role in the synthesis of neurotransmitters such as serotonin, dopamine, and GABA. A deficiency in pyridoxine can lead to decreased synthesis of these neurotransmitters, particularly GABA, which is an inhibitory neurotransmitter in the central nervous system. This imbalance can lead to neuronal hyperexcitability, resulting in symptoms like irritability, depression, and in severe cases, convulsions or seizures.