Question:

Deficiency of the enzyme phenylalanine hydroxylase causes Phenylketonuria. Phenylalanine hydroxylase converts phenylalanine to

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In Phenylketonuria, phenylalanine hydroxylase deficiency prevents the conversion of phenylalanine to tyrosine, leading to its accumulation.
Updated On: Dec 2, 2025
  • tryptophan
  • alanine
  • tyrosine
  • threonine
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the condition.
Phenylketonuria is a metabolic disorder where the body cannot properly convert phenylalanine to tyrosine due to a deficiency in the enzyme phenylalanine hydroxylase.

Step 2: Analyzing the options.
(A) tryptophan: This is incorrect; phenylalanine is not converted to tryptophan.
(B) alanine: This is incorrect; phenylalanine is not converted to alanine.
(C) tyrosine: Correct — phenylalanine is converted to tyrosine by the enzyme phenylalanine hydroxylase.
(D) threonine: This is incorrect; phenylalanine is not converted to threonine.

Step 3: Conclusion.
The correct answer is (C) tyrosine.

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