Question

Cyclosporin A is a drug that

• A. suppresses the immune system
• B. increases body temperature
• C. increases the production of antibodies
• D. decreases body temperature

Answer 1

The Correct Option is A

Cyclosporin A is an immunosuppressive drug that is widely used to prevent organ transplant rejection and in autoimmune diseases. 

Step 1: Mechanism of Action - Cyclosporin A is a calcineurin inhibitor. - It binds to cyclophilin, forming a complex that inhibits calcineurin, a protein required for T-cell activation. - By inhibiting calcineurin, Cyclosporin A suppresses the activation of T-cells, reducing the immune response. 

Step 2: Evaluating the Options - Option (A) - Correct: Cyclosporin A suppresses the immune system by inhibiting T-cell activation. 
- Option (B) - Incorrect: Cyclosporin A does not increase body temperature; it regulates immune activity. 
- Option (C) - Incorrect: It does not increase antibody production; instead, it reduces immune responses. 
- Option (D) - Incorrect: It does not decrease body temperature. 

Step 3: Conclusion Since Cyclosporin A is an immunosuppressive drug used in transplant patients and autoimmune diseases, the correct answer is option (A).