Question:

Cryoglobulinemia

Updated On: Jul 12, 2025
  • Hepatitis c
  • Ovarian cancer
  • Diabetes
  • Leukemia
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The Correct Option is A

Solution and Explanation

Cryoglobulinemia is a medical condition characterized by the presence of abnormal proteins, called cryoglobulins, in the blood that can precipitate at cold temperatures. It is associated with several underlying conditions.
The provided options for the association with cryoglobulinemia are:
  • Hepatitis C
  • Ovarian cancer
  • Diabetes
  • Leukemia
The correct association is with Hepatitis C. Here's why:
Explanation:Cryoglobulinemia has a well-known association with chronic infections, particularly chronic viral hepatitis. Among these, Hepatitis C virus (HCV) is the most commonly associated condition. HCV infection leads to mixed cryoglobulinemia, where immune complexes, made up of the virus and antibodies formed in response, precipitate at lower temperatures.
While cryoglobulinemia can be associated secondarily with some cancers and autoimmune conditions, Hepatitis C remains the most prevalent and significant cause.
This knowledge is especially pertinent in pediatrics where early identification and management of chronic Hepatitis C can prevent complications related to cryoglobulinemia.
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