Question:

Correctly match the following Bioinformatic tool/Database with its respective Utility.


 

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Bioinformatic tools like BLAST, Bowtie, and AlphaFold play critical roles in sequence alignment, structure prediction, and understanding molecular biology.
Updated On: Apr 11, 2025
  • P-2; Q-3; R-1; S-4
  • P-2; Q-3; R-4; S-1
  • P-3; Q-2; R-4; S-1
  • P-4; Q-1; R-2; S-3
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The Correct Option is B

Solution and Explanation

Step 1: Understand the function of each tool/database.

BLAST (P): Used to find regions of local similarity between sequences. It identifies similarity between a query sequence and existing sequences in databanks.

Bowtie (Q): A tool for aligning short read DNA sequences obtained from next-generation sequencing to a reference genome.

AlphaFold (R): An AI-based tool designed to predict protein structures from amino acid sequences.

PDB (S): The Protein Data Bank, a repository of 3D structures of proteins.

Step 2: Match the tools with their utilities.

P - 2: BLAST → Identifies similarity of a query sequence to existing sequences in databanks.
Q - 3: Bowtie → Aligns short read DNA sequences to a reference genome.
R - 4: AlphaFold → Predicts protein structures using AI.
S - 1: PDB → Database for 3D protein structures.

Final Answer:
The correct answer is \( \boxed{(B)} \).
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