The given function is:
\[
u(x, y) = e^{2x}[\sin 3x \cos 2y \cosh 3y - \cos 3x \sin 2y \sinh 3y].
\]
To find \( f(z) \), we first compute \( u(x, y) \) and its harmonic conjugate \( v(x, y) \), which are related by the Cauchy-Riemann equations. We are asked to find the value of \( 4 + 2i f(i\pi) \). First, evaluate \( u(x, y) \) and \( v(x, y) \) at \( z = i\pi \). After calculations, the value of \( 4 + 2i f(i\pi) \) results in:
\[
- e^{3\pi} + e^{-3\pi}.
\]
Thus, the correct answer is \( \boxed{-e^{3\pi} + e^{-3\pi}} \).