Step 1: Introduction.
Gregor Johann Mendel, known as the "Father of Genetics," performed hybridization experiments on pea plants (Pisum sativum). His work explained how traits are passed from one generation to the next.
Step 2: Experimental Work.
- Mendel chose pea plants because they had distinct, contrasting traits (like tall/dwarf, round/wrinkled).
- He conducted monohybrid and dihybrid crosses.
- By analyzing the offspring, he discovered patterns of inheritance.
Step 3: Contributions (Laws).
1. Law of Segregation: Each individual carries two alleles for a trait, which segregate during gamete formation, ensuring each gamete receives one allele.
2. Law of Independent Assortment: Alleles of different traits assort independently during gamete formation.
3. Law of Dominance: When two contrasting alleles are present, one dominates (dominant trait) while the other is masked (recessive).
Step 4: Impact.
Although Mendel's work was initially ignored, it was rediscovered in 1900 by Hugo de Vries, Correns, and von Tschermak. His principles became the foundation of classical genetics.
Final Answer:
\[
\boxed{\text{Mendel discovered the fundamental laws of inheritance through pea plant experiments.}}
\]
1. Perform a cross between two sickle cell carriers. What ratio is obtained between carrier, disease free and diseased individuals in F1 progeny? Name the nitrogenous base substituted, in the haemoglobin molecule in this disease.
2. Explain the difference in inheritance pattern of flower colour in garden pea plant and snap-dragon plant with the help of monohybrid crosses.
OR,
Explain with the help of well-labelled diagrams how lac operon operates in E. coli :
1. In presence of an inducer.
2. In absence of an inducer.
Study the pedigree chart given below, showing the inheritance pattern of blood group in a family:

Answer the following questions:
(a) Give the possible genotypes of individual 1 and 2.
(b) Which antigen or antigens will be present on the plasma membranes of the R.B.Cs of individuals ‘5’ and ‘8’?
The sequence of nitrogenous bases in a segment of a coding strand of DNA is
5' – AATGCTAGGCAC – 3'. Choose the option that shows the correct sequence of nitrogenous bases in the mRNA transcribed by the DNA.