Question

Chemical nature of primers of DNA/RNA

• A. Oligosaccharides
• B. Oligonucleotides
• C. Polypeptides
• D. Disaccharides

Hint:

Primers are always nucleotides (DNA/RNA), not proteins or simple sugars. Oligonucleotides are typically 10–20 bases long in PCR and replication.

Answer 1

The Correct Option is B

Primers for DNA replication and transcription are short nucleic acid sequences (oligonucleotides) that provide a free 3′-OH group for DNA polymerase or RNA polymerase to extend. Polypeptides or sugars cannot act as primers.