Question:

Cerebral blood flow is regulated by all except:

Updated On: Jul 15, 2025
  • Blood pressure
  • Arterial PCO2
  • Potassium ions
  • A & C
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The Correct Option is D

Solution and Explanation

The regulation of cerebral blood flow is a critical physiological process influenced by various factors. Among the listed options:

  • Blood pressure: Cerebral blood flow is regulated by mechanisms such as autoregulation, which maintains a consistent blood flow despite changes in systemic blood pressure. Therefore, blood pressure is indeed a regulator of cerebral blood flow.
  • Arterial PCO2: Levels of carbon dioxide in the blood play a pivotal role in the regulation of cerebral blood flow. An increase in arterial PCO2 leads to vasodilation and increased blood flow, while a decrease causes vasoconstriction and reduced flow. Thus, arterial PCO2 is a regulator.
  • Potassium ions: Potassium ions influence various cellular functions but are not primary regulators of cerebral blood flow.
  • A & C: This option suggests that blood pressure and potassium ions are not regulators. Since potassium ions are not directly involved, this option is correct as both A (blood pressure) and C (potassium ions) are not the ones left from the regulatory factors mentioned.

The correct choice is: A & C, as blood pressure and potassium ions are either regulated by other processes or are not primary regulators of cerebral blood flow.

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