Question:

CD59 marker of which disease

Updated On: Jul 12, 2025
  • PNH
  • PTEN
  • BRR
  • Cowden syndrome
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The Correct Option is A

Solution and Explanation

The CD59 marker is associated with the disease Paroxysmal Nocturnal Hemoglobinuria (PNH). CD59 is a protein that regulates the complement system by inhibiting the formation of the membrane attack complex (MAC) on cell surfaces. In PNH, a genetic mutation affects the surface proteins that normally anchor CD59, leading to an increased susceptibility of red blood cells to be lysed by the complement system.

DiseaseAssociated Marker
PNHCD59
PTENNot associated
BRRNot associated
Cowden syndromeNot associated
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