Question

Captisol is an excipient based on:

• A. \( \text{PLA polymer} \)
• B. \( \text{PLGA polymer} \)
• C. \( \text{Cyclodextrin} \)
• D. \( \text{PEG} \)

Hint:

Cyclodextrin-based excipients are valuable in drug formulation due to their ability to enhance bioavailability of poorly water-soluble drugs.

Answer 1

The Correct Option is C

Captisol is a chemically modified form of cyclodextrin used to enhance the solubility and stability of drugs. Cyclodextrins have a hydrophobic cavity that improves drug delivery by encapsulating poorly soluble compounds. Its application has been widely adopted in formulation sciences for injectable medications.