Question

Calcitonin levels increased in:

• A. Hyperthyroidism
• B. Hyperparathyroidism
• C. Hypoparathyroidism
• D. Cushing Syndrome

Answer 1

The Correct Option is B

In understanding the relationship between calcitonin levels and various endocrine disorders, it's crucial to examine the physiological roles these hormones play.

Calcitonin is a hormone secreted by the parafollicular cells (also known as C cells) of the thyroid gland. Its primary function is to decrease blood calcium levels by inhibiting osteoclast activity in the bones and reducing calcium reabsorption in the kidneys.

Among the conditions listed:

• Hyperthyroidism: This condition involves an overactive thyroid gland producing excessive thyroid hormones, but it does not directly affect calcitonin levels.
• Hyperparathyroidism: This condition is characterized by excessive secretion of parathyroid hormone (PTH), which increases blood calcium levels. In response to hypercalcemia, the body may increase calcitonin production to counteract the high blood calcium levels.
• Hypoparathyroidism: This results in low levels of parathyroid hormone, leading to decreased blood calcium levels, often accompanied by low calcitonin levels.
• Cushing Syndrome: Characterized by high levels of cortisol, this condition does not primarily affect calcitonin levels.

Therefore, calcitonin levels are increased in Hyperparathyroidism as a physiological response to regulate elevated blood calcium levels.