In the field of Gynaecology and Obstetrics, prenatal screening tests play a crucial role in assessing the health of a developing fetus. The quadruple test, often called the quad screen, is one such important screening test. It measures four substances in a pregnant woman's blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), estriol, and inhibin A. These markers help identify the risk of certain birth defects, such as Down syndrome and neural tube defects.
During a typical pregnancy, the levels of these substances change at different stages. Therefore, for the quadruple test to provide accurate and useful results, it must be conducted during the optimal time frame.
The recommended period for conducting the quadruple test is between 15-20 weeks of gestation. Testing during this window allows clinicians to obtain the most reliable results, giving expecting parents and healthcare providers the opportunity to make informed decisions about further diagnostic testing or interventions, if necessary.
A female patient presents to you with six weeks of amenorrhea, associated with abdominal pain and vaginal bleeding with normal blood pressure. Investigations revealed beta – hCG to be 1400 mIU/mL. An ultrasound scan was done which showed a trilaminar endometrium with normal adnexa. What is the next best step in the management of this patient ?
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