Question

A 20 year old woman presented at 7 weeks of gestation, unwilling to continue the pregnancy. What are the drugs used for medical termination of pregnancy in this patient?

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• A. Misoprostol and Medroxyprogesterone
• B. Misoprostol and Mifepristone
• C. Mifepristone and Methotrexate
• D. Mifepristone and Medroxyprogesterone

Answer 1

The Correct Option is B

In the context of medical termination of pregnancy, particularly in a patient at 7 weeks of gestation, the combination of Misoprostol and Mifepristone is commonly used. This regimen is effective and widely accepted for early gestational termination.

Explanation:

• Mifepristone is an antiprogestogen that works by blocking the action of progesterone, a hormone necessary for maintaining pregnancy. By inhibiting this hormone, it leads to changes in the uterine lining and detachment of the embryo.
• Misoprostol is a prostaglandin E1 analog that induces uterine contractions and further aids in the expulsion of the pregnancy. It is typically administered after Mifepristone to ensure complete termination.

The combination of these two drugs is highly effective when used within the first trimester of pregnancy. Other options listed either do not correspond to the standard practice or involve drugs not usually combined for this purpose.