Question

Best antigen presenting cell is

• A. Mast cell
• B. B cell
• C. Neutrophils
• D. Dendritic cells

Hint:

• Professional Antigen-Presenting Cells (APCs): Dendritic cells, Macrophages, B cells.
• They express MHC class II molecules (for presenting to CD4+ T helper cells) and MHC class I molecules (on all nucleated cells, for presenting to CD8+ cytotoxic T cells).
• Dendritic cells are particularly specialized and efficient at capturing antigens in peripheral tissues and migrating to lymphoid organs to activate naive T cells.

Answer 1

The Correct Option is D

Best Antigen Presenting Cell: Dendritic Cells

Antigen presenting cells (APCs) are crucial in the immune system as they process antigens and present them on their surface to T cells. Among the various types of APCs, dendritic cells are considered the most potent.

• Dendritic Cells: These cells are the most efficient and effective APCs. They have a high capacity to capture, process, and present antigens. Dendritic cells are responsible for capturing antigens in peripheral tissues and are key in activating naive T cells, thereby initiating the adaptive immune response.
• B Cells: While B cells can act as antigen presenting cells, they primarily function in the production of antibodies. Their APC function is secondary to that of dendritic cells.
• Mast Cells and Neutrophils: These cells are not primarily known for their antigen presenting capabilities. Mast cells play a role in allergic responses, while neutrophils are key players in innate immunity and primarily act as phagocytes rather than APCs.

In summary, dendritic cells are the best and most proficient antigen presenting cells, playing a critical role in the communication between the innate and adaptive immune systems.