Question

Assertion (A): In molecular diagnosis, single stranded DNA or RNA tagged with radioactive molecule is called a probe.
Reason (R): A probe always searches and hybridises with its complementary DNA in a clone of cells.

• A. Both (A) and (R) are true and (R) is the correct explanation of (A).
• B. Both (A) and (R) are true, but (R) is not the correct explanation of (A).
• C. (A) is true, but (R) is false.
• D. (A) is false, but (R) is true.

Hint:

Probes are used in techniques like Southern blotting to detect specific DNA sequences.

Answer 1

The Correct Option is A

- Probes are single-stranded DNA or RNA molecules tagged with radioactive or fluorescent labels used in molecular diagnostics. - They specifically hybridise with complementary sequences in the target DNA, enabling detection in molecular diagnostic techniques.