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Aquapheresis in acute decompensated heart failure (ADHF).

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Aquapheresis is an effective option for managing fluid overload in ADHF, particularly when diuretics fail, but it requires careful monitoring of the patient.
Updated On: Dec 11, 2025
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Solution and Explanation

Aquapheresis, also known as ultrafiltration, is a process used to remove excess fluid from the body in patients with acute decompensated heart failure (ADHF).
Step 1: Mechanism of Action:
Aquapheresis works by using a machine to filter excess fluid from the blood, which is then removed via a catheter. This procedure helps alleviate symptoms of fluid overload, such as pulmonary edema, in patients with heart failure.
Step 2: Indications for Aquapheresis:
1. Fluid Overload in ADHF: It is primarily used in patients with severe ADHF who are not responding adequately to diuretics.
2. Diuretic Resistance: In patients with diuretic resistance, aquapheresis can be a useful alternative to help remove excess fluid.
Step 3: Benefits and Risks:
1. Benefits: Aquapheresis can improve hemodynamics, reduce symptoms of congestion, and improve exercise capacity.
2. Risks: Potential risks include hypotension, electrolyte imbalances, and vascular complications due to the catheter.
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