Question

Absolute solubility does not rely on standard condition of:

• A. pH
• B. Pressure
• C. Temperature
• D. Volume

Answer 1

The Correct Option is A

To determine the factor on which absolute solubility does not rely, we need to understand the concept of solubility in physical pharmacy.

Solubility is the ability of a solute to dissolve in a solvent. Solubility can depend on several factors, commonly including pressure, temperature, and volume. However, solubility can be independent of certain conditions such as pH in some contexts.

1. Temperature: Solubility often depends on temperature. Generally, solubility of solids in liquid solvents increases with an increase in temperature.
2. Pressure: Solubility of gases in liquids significantly depends on pressure. According to Henry's law, increasing the pressure can increase the solubility of a gas in a liquid.
3. Volume: While volume itself is directly related to the state of the solvent, changing volume without altering pressure or temperature does not independently affect solubility.
4. pH: The solubility of a substance is not fundamentally dependent on pH under standard physical conditions. However, pH can affect the ionization state of a solute, which in turn can affect solubility in a secondary manner rather than directly altering solubility as a primary condition.

Given these explanations, the correct answer to the question regarding which standard condition absolute solubility does not rely on is pH. pH can influence solubility in certain situations (like weak acids and bases), but it is not a basic standard condition affecting solubility across all substances.