What is the difference between native protein and denatured protein?
What is the difference between native protein and denatured protein?
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Solution and Explanation
Native vs. Denatured Proteins
Native Proteins:
- These are proteins in their natural, biologically active form.
- They possess a specific three-dimensional structure essential for their function.
- Their structure includes well-defined secondary, tertiary, and sometimes quaternary levels of organization.
- This conformation is stabilized by:
- Hydrogen bonds
- Hydrophobic interactions
- Disulfide bridges
- Ionic interactions
Denatured Proteins:
- These proteins have lost their native conformation and, as a result, their biological activity.
- Denaturation involves the disruption of stabilizing forces, leading to the unfolding of the protein structure.
- Causes of denaturation include:
- High or low temperature
- pH changes
- Chemical agents (e.g., urea, detergents)
- Denatured proteins are typically inactive and may become insoluble or form aggregates.
In summary, the functional integrity of a protein is closely tied to its native conformation. Disruption of this structure results in a loss of function.
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Questions Asked in CBSE CLASS XII exam
- Let \( \vec{a} \) be a position vector whose tip is the point (2, -3). If \( \overrightarrow{AB} = \vec{a} \), where coordinates of A are (–4, 5), then the coordinates of B are:
- Your school is organizing a road safety awareness workshop for students of class IX – XII. As the head boy of your school, draft a notice informing the students about the workshop. Include other necessary details. You are Ashna/Ashish. Put your notice in a box.
- CBSE CLASS XII - 2025
- Letter Writing
Read the following passage carefully:
(1) Gossip. All humans partake in some form, despite the age-old adage, "If you have nothing nice to say, don't say anything at all." Whether it's workplace chatter, the sharing of family news or group texts between friends, it's inevitable that anyone who participates in the above, talks about other people.
(2) People tend to think of gossip as synonymous with malicious rumours, put-downs, or the breathless propagation of a tabloid scoop. But researchers often define it more broadly as "talking about people who aren't present," says an assistant professor of psychology. "It's something that comes very naturally to us" - an integral part of conversation, information sharing, and even community building.
(3) "It's not necessarily negative," adds a professor of psychology. "It can be positive or neutral." Some researchers argue that gossip helped our ancestors survive. Evolutionary psychologists first pioneered this idea, comparing gossip to the grooming primates engage in as a means of bonding.
(4) People are usually resistant to thinking about gossip as anything but bad. It is true that there are some types of gossip that should be avoided, such as gossip that is purely harmful and serves no purpose like mean comments on someone's way of dressing. In such a scenario no one benefits. Gossip can also be both active and passive. Active gossiping refers to directly sharing negative information about someone else. An active gossiper initiates the conversation and actively spreads it. Passive gossiping on the other hand involves more subtle behaviour like hinting, dropping suggestive comments or participating in gossip by listening without actively contributing, but still allowing the gossip to spread through their presence.
(5) It's interesting to note that gossiping also says something about relationships people have with one another. The act of gossiping often implies a level of trust and closeness with someone, which are key aspects of a good friendship.
(6) Research has found that gossip can stave off loneliness, while other studies have found it can facilitate bonding and closeness and serve as a form of entertainment. So, keep on talking. And when your conversation turns to gossip, as it inevitably will, remember that some good can come of it - with the right intentions, of course.
Answer the following questions, based on the above passage:- CBSE CLASS XII - 2025
- Reading Comprehension
Read the following passage carefully:
(1) Introduction: Humans are social creatures with a deep desire to interact with one another. Recent developments in technology have made it possible for billions of people worldwide to use cell phones to satisfy this need. The current study aims to analyse the impact of smartphone use among various categories of people in Kerala, India. The present study will provide an insight into the extent and magnitude of people's reliance on smartphones to communicate in this modern age and the dwindling nature of social relationships.
(2) Methodology: A google form created questionnaire was used to gather information on the subject from a sample of participants who were from various districts in Kerala, India.
(3) Survey Examination: Among the 131 study participants, 66 were men and the remaining 65 were women. For convenience, the study considered only the main purpose for which a smartphone is used by any given individual.
(4) Results:
Individuals differed in their interests and preferences regarding their choice of communication medium. Some preferred direct conversation, while others conveyed their messages through virtual mediums of communication, that did not involve any face-to-face interaction.
(5) Implications for Interventions: It was observed that individuals were interested in using their smartphones even when they were dining. This constant use can have several disadvantages such as reckless use of mobile phones, including prolonged hours of radiation exposure, over-calorie intake due to binge eating, leading to obesity, and other health problems. It is also a vital tool to achieve social progress.
The use of phones while travelling can sometimes detract from an individual's enjoyment of the serenity of the environment, the scenic beauty of picnic spots, and affect the way an individual behaves and interacts with his or her co-travellers.
(6) Conclusion: It is true that most of the population under different age and gender categories use smartphones every day, but there is no significant fall in the duration spent in direct face-to-face conversation with fellow beings, except in very few individuals. The majority of people agree that traditional face-to-face communication is more comfortable, reliable, and expressive than text messages, phone calls, or electronic mail.
Answer the following questions, based on the above passage:- CBSE CLASS XII - 2025
- Reading Comprehension
Read the following extracts and answer the questions
Aunt Jennifer's fingers fluttering through her wool
Find even the ivory needle hard to pull.
The massive weight of Uncle's wedding band
Sits heavily upon Aunt Jennifer's hand.
When Aunt is dead, her terrified hands will lie
Still ringed with ordeals she was mastered by.
The tigers in the panel that she made
Will go on prancing, proud and unafraid.
(Aunt Jennifer's Tigers)