Question

A tuberculosis patient on anti-tubercular treatment presents with a tingling sensation and paresthesia in the lower limbs. He is not a diabetic and occasionally consumes alcohol. Which of the following vitamins must be supplemented to this patient?

• A. Vitamin B6
• B. Vitamin B12
• C. Vitamin B2
• D. Vitamin B3

Answer 1

The Correct Option is A

The patient's symptoms, tingling sensation and paresthesia in the lower limbs while on anti-tubercular treatment, suggest the development of peripheral neuropathy. This is a known side effect of Isoniazid, a common medication used in tuberculosis treatment. Isoniazid can induce neuropathy due to its interference with pyridoxine (Vitamin B6) metabolism. Supplementation with Vitamin B6 is crucial to prevent or treat this condition.

The patient is not diabetic, which is a common cause of peripheral neuropathy, and the consumption of alcohol, being occasional, is unlikely the main cause here. Therefore, the most appropriate course of action is to supplement Vitamin B6.

In summary, to address the neuropathic side effects of anti-tubercular treatment in this patient, Vitamin B6 needs to be supplemented.