Question

A pregnant woman with a history of bronchial asthma is in the third stage of labor. Which drugs should be avoided in managing postpartum hemorrhage in this mother?

• A. Carboprost
• B. Oxytocin
• C. Dinoprostone
• D. Methyl ergometrine

Answer 1

The Correct Option is A

In managing postpartum hemorrhage (PPH) for a pregnant woman with a history of bronchial asthma, it's crucial to avoid drugs that may exacerbate asthma symptoms. Bronchial asthma is a condition where certain medications can induce bronchoconstriction, leading to severe respiratory issues.

Among the options:

• Carboprost: A prostaglandin analog that is known to cause bronchoconstriction. It is contraindicated in patients with asthma due to its potential to trigger severe asthmatic episodes.
• Oxytocin: Generally considered safe in asthma and is commonly used for PPH management.
• Dinoprostone: While it can have some bronchoactive effects, it is less commonly associated with severe bronchospasm when compared to carboprost.
• Methyl ergometrine: Primarily avoided due to its vasoconstrictive effects, it is less concerning in the context of bronchial issues.

Given this information, the drug that should definitely be avoided in this scenario due to the risk of bronchospasm is Carboprost.