Question

A girl child has had recurrent yeast & respiratory virus infection since she was 3 months old. Now considering studies for immune status, which vaccine is contraindicated?

• A. TT/Td
• B. Measles/MMR
• C. DPT
• D. Killed IPV

Answer 1

The Correct Option is B

In the context of immunization and recurrent infections, it is crucial to understand which vaccines are contraindicated for certain individuals. A child with recurrent yeast and respiratory infections may have an underlying immune deficiency, making them potentially unable to handle live vaccines.

Live vaccines contain a weakened form of the virus or bacteria and rely on the body’s immune system to build protection without causing the actual disease. However, in immunocompromised individuals, these vaccines can cause the disease they are meant to prevent.

Among the vaccines mentioned:

• TT/Td (Tetanus Toxoid/Tetanus-Diphtheria): These are inactivated vaccines and are not contraindicated in individuals with immune deficiencies.
• DPT (Diphtheria, Pertussis, Tetanus): This vaccine also includes inactivated components and is generally safe for immunocompromised individuals.
• Killed IPV (Inactivated Polio Vaccine): As an inactivated vaccine, it is safe for children who may have immune system deficiencies.
• Measles/MMR (Measles, Mumps, Rubella): This is a live attenuated vaccine and can cause issues for those with impaired immune systems. Hence, it is contraindicated for children like the one described in the situation due to the risk of adverse effects.

Therefore, the vaccine contraindicated in this case is Measles/MMR, due to its live attenuated formulation, posing a risk to an immunocompromised child.