Question

A 26 years old male with backache, morning stiffness, chest expansion and reddening of eyes with an X-ray presented in OPD. Most likely diagnosis for this patient is

• A. Rheumatoid arthritis
• B. Ankylosing spondylitis
• C. . Paget’s disease
• D. Osteopetrosis

Answer 1

The Correct Option is B

The patient's symptoms suggest a specific condition. Let's analyze each symptom for a precise diagnosis:

• Backache and Morning Stiffness: Common in inflammatory conditions, particularly affecting the spine.
• Chest Expansion: Limited chest expansion can indicate a condition affecting the spine and rib joints.
• Reddening of Eyes: Indicates possible uveitis, often associated with systemic inflammatory diseases.

Given these symptoms and their associations, we evaluate the options:

• Rheumatoid arthritis: Primarily affects peripheral joints, not typically associated with chest expansion or significant backache.
• Ankylosing spondylitis: Affects the spine, causing backache, morning stiffness, and reduced chest expansion. Uveitis is a recognized association.
• Paget’s disease: Usually involves abnormal bone remodeling, unlikely to cause morning stiffness or eye symptoms directly.
• Osteopetrosis: Characterized by increased bone density, not directly linked to these symptoms.

Considering the symptomatology and associations, the most likely diagnosis for the patient is Ankylosing spondylitis, as it encompasses the spine symptoms, eye involvement, and reduced chest expansion.