5-year male child present to the clinic with H/O recurrent infection On examination he was found to have rashes shown below in the image. On routine blood investigation, low platelet count was found what will be the diagnosis ?
Pediatrics question focusing on the diagnosis of a condition in a child presenting with recurrent infections, rashes, and thrombocytopenia. A 5-year-old male child presents with these symptoms: recurrent infections, identifiable rashes (visible in an accompanying image), and a low platelet count on routine blood tests.
To accurately diagnose this condition, let's examine each clue:
Recurrent Infections: This suggests an issue with the immune system.
Rashes: May be due to an underlying immunological disorder.
Low Platelet Count: Also known as thrombocytopenia, it indicates a potential issue with blood clotting.
Let's break down the possible conditions:
Wiskott Aldrich Syndrome: This is characterized by the triad of eczema (rashes), recurrent infections due to immunodeficiency, and thrombocytopenia. It is an X-linked recessive condition, typically presenting in male children.
Job's Syndrome: Known as Hyper-IgE syndrome, it involves recurrent infections and eczema but not thrombocytopenia.
Chediak Higashi Syndrome: Affects lysosomal trafficking, causing recurrent infections and partial oculocutaneous albinism, with bleeding tendencies, but is less classically associated with the triad mentioned here.
None: Indicates none of the conditions fit the symptoms accurately.
Given the specific symptoms presented by the child—recurrent infections, rashes, and a low platelet count—the most fitting diagnosis is:
