Question:
2n-1 condition is:
2n-1 condition is:
Updated On: Sep 3, 2024
- nullisomy
- monosomy
- trisomy
- tetrasomy
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The Correct Option is B
Approach Solution - 1
2n-1 condition is monosomy in which one chromosome has been lost.
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Solution: The correct option is (B): Monosomy
Explanation:
- Monosomy is a type of aneuploidy, signifying an imbalance in the number of chromosomes.
- This condition indicates that cells either have an extra chromosome or are lacking one.
- The formula for monosomy is given as 2n – 1, where n is a normal chromosome number present in a set.
- A normal diploid chromosome count (2n) is considered normal and a pair of one missing chromosome results in 45 chromosomes, potentially leading to abnormalities.
Therefore, the formula for human monosomy would be 2(23) - 1, yielding 45 chromosomes.
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Concepts Used:
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Chromosomal theory: Linkage and Genetic Recombination
If two genes were present on the same chromosome, the chances of getting a parental combination were much higher in the next generation in comparison to the non-parental combination. This physical association of genes was termed ‘linkage’. The description of the non-parental gene combinations in a dihybrid cross is termed ‘genetic recombination'. After the discovery of linked genes, the frequency of linked genes also influenced the appearance of traits in the next generation.
Observations of Chromosomal Theory of Inheritance:
- During the cell division-meiosis process, the pairs of homologous chromosomes move as discrete structures, which are independent of other pairs of chromosomes.
- From each homologous pair, there is a random distribution of chromosomes into the pre-gametes.
- Each parent synthesizes gametes, which add up to only half of their chromosomal complement.
- Even though female (egg) and male (sperm) gametes differ in morphology and size, they have the same number of chromosomes, submitting equal genetic contributions from each parent.
- The gametic chromosomes fuse during the process of fertilization to produce offspring with the same number of a chromosome as their parents.
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